神经肌肉骨骼功能在维持正常步态模式中相互作用。脚的姿势和结构的改变是疾病的结果。例如，糖尿病会影响跑步的生物力学和脚部负重。我们进行了一项前瞻性横断面研究，以评估2型糖尿病患者足部解剖改变的危险因素。在埃塞俄比亚西南部的米赞特比大学教学医院，对196名正常受试者进行了研究。数据收集采用结构良好的问卷和糖尿病足评估检查表。数据分析采用SPSS 24版本。随机选择相关危险因素采用多元线性回归模型进行评估。我们的结果显示，与糖尿病相关的足部畸形的发生率在7-12%之间变化。这些畸形包括7%的高足，8.5%的趾外翻，9%的老茧和12%的爪状/锤状趾。 We also demonstrated diabetic related chronic complications: 44.9% foot ulcer, 20.4% peripheral neuropathy, and 18.4% peripheral arterial disease. Duration of diabetes (r= 0.026, p≤0.032) and drinking alcohol (r=0.143, p≤0.007) were significantly and directly associated with diabetic foot deformity. Occupation (r= -0.157, p≤0.003), types of diabetes (r= -0.172, p≤0.002), and presence of neurological symptoms (r= -0.120, p≤0.020) was inversely associated with diabetic foot deformity. We concluded that Hammer/Claw toe was found to be the most prevalent foot deformities among Ethiopians participating in this study and the majority of the study participants did not understand the effect of diabetes on foot health. We found only 18.4% patients were aware of the effects of diabetes on foot health, where 15.8% subjects were identified with appropriate foot care practice mobility among the study population.